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Biologica bei Psoriasis und Psoriasis Arthritis - Versuch einer Übersicht

GrBaer185

2,277 views

Die folgenden Tabellenelemente sind dem Wikipedia-Artikel
https://de.wikipedia.org/wiki/Monoklonaler_Antikörper
entnommen.

Name Handelsname Typ Zielstruktur Anwendungsgebiet

.

Efalizumab Raptiva humanisiert CD11a-Antigen Psoriasis

.

Golimumab Simponi human TNF-α (Tumor Necrosis Factor α) Colitis ulcerosa, Rheumatoide Arthritis, Psoriasis-Arthritis, Morbus Bechterew
Infliximab Remicade chimär TNF-α (Tumor Necrosis Factor α) Morbus Crohn, Rheumatoide Arthritis, Morbus Bechterew, Psoriasis-Arthritis, Colitis ulcerosa
Adalimumab Humira human TNF-α (Tumor Necrosis Factor α) Rheumatoide Arthritis, Psoriasis-Arthritis, Morbus Bechterew, Morbus Crohn

.

Secukinumab Cosentyx (Novartis) human Interleukin-17A-Rezeptor Psoriasis, Psoriasis-Arthritis, Morbus Bechterew
Brodalumab1,2 Kyntheum (LEO Pharma) human Interleukin-17-Rezeptor Psoriasis, Psoriasis-Arthritis, Asthma
Ixekizumab Taltz humanisiert Interleukin-17A-Rezeptor (IL-17A) Psoriasis, Psoriasis-Arthritis

.

Guselkumab1,2 Tremfya

(Janssen)

human Anti-Interleukin-23 Psoriasis, Rheumatoide Arthritis
Risankizumab1,2 Skyrizi (AbbVie) humanisiert Interleukin-23-Rezeptor Psoriasis[18], Psoriasis-Arthritis, Morbus Crohn

.

Ustekinumab Stelara human Interleukin 12/23 Plaque-Psoriasis
Briakinumab   p40-Untereinheit von Interleukin-12 (IL-12) und Interleukin-23 (IL-23) Psoriasis Zulassungsantrag von Abbott zurückgezogen

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.

Im Folgenden eine interessante Übersicht aus der englischen Wikipedia (dort noch übersichtlicher und Links aktiviert) -
siehe unter folgendem Link 
https://en.wikipedia.org/wiki/Interleukin_17
dort  auf der Internetseite ganz unten bei "Interleukin receptor Modulators" ganz rechts auf "show" klicken.

IL-1
IL-2
IL-3
IL-4
IL-5
IL-6
IL-7
IL-8
  • See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead.
IL-9
IL-10
IL-11
IL-12
IL-13
IL-15
IL-17
IL-18
IL-20
IL-21
IL-22
IL-23
IL-27
IL-28
IL-31
IL1RL1
IL1RL2
Others
 
JAK
Others
 

 

 



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